A key principle of individual differences research is that genetic and environmental factors jointly influence personality and psychopathology. Genes and environments interact to influence the emergence and stability of both normal and maladaptive behavior, including by shaping the neural circuits underpinning behavior. However, genetic factors are not independent from environmental influences. That is, individuals may experience environments that correlate with heritable risk (e.g., parenting influences can reflect shared genetic predispositions of parents and children). Throughout our program of research, we aim to separate out the influences of genetics, personality, psychopathology, neural function and structure, and environment. This focus is important for how we design and target treatment and intervention.
Relevant peer-reviewed publications
- Perlstein, S., Hawes, S., Vazquez, A.Y., Pacheco-Colón, I., Lehman, S., Parent, J., Byrd, A., & Waller, R.^ (2022). Genetic versus environmental influences on callous-unemotional traits in preadolescence: the role of parenting and parental psychopathology. Development and Psychopathology, 34, 1686-1701
- Perlstein, S. & Waller, R.^ (2022). Integrating the Study of Personality and Psychopathology in the Context of Gene-Environment Correlations Across Development. Journal of Personality, 90, 47-60
- Waller, R., Hyde, L.W., Klump, K.L., & Burt, S.A. (2018). Parenting Is an Environmental Predictor of Callous-Unemotional Traits and Aggression: A Monozygotic Twin Differences Study. Journal of the American Academy of Child and Adolescent Psychiatry, 57, 955-963
- Waller, R., Trentacosta, C.J., Shaw, D.S., Neiderhiser, J.M., Ganiban, J.M., Reiss, D., Leve, L.D., & Hyde, L.W. (2016). Heritable Temperamental Precursors of Early Callous-Unemotional Behavior. British Journal of Psychiatry, 209, 475-482
- Hyde, L. W., Waller, R., Trentacosta, C. J., Shaw, D. S., Neiderhiser, J. M., Ganiban, J. M., … & Leve, L. D. (2016). Heritable and nonheritable pathways to early callous-unemotional behaviors. American Journal of Psychiatry, 173, 903-910
- Swartz, J.R., Waller, R., Knodt, A.R., Sabhlok, A., Hyde, L.W., & Hariri, A.R. (2016). A Common Polymorphism in The Williams Syndrome Gene GTF2I Predicts Threat-Related Amygdala Reactivity and Socioemotional Behavior in Healthy Young Adults. Biological Psychiatry, 81, 203-210

